0 Comments | Apr 23, 2011

Zetaclear Review: Pros And Cons For Nail Fungus Treatment

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Nail fungus infections (also known as tinea unguium or Onychomycosis) affect between 8-12% of the population.  While generally not considered a dangerous or life threatening disease, the condition is embarrassing and, if left to advance to the point where the infected nail separates from the nail base, can result in disfigurement and impaired movement.  Oral antifungal medications are available on prescription, but as side effects are common, including heart and liver damage, most sufferers choose alternative treatments that are applied externally to affected nails.

One of the best selling topical treatments is Zetaclear nail fungus treatment.  It is marketed aggressively in the US and contains Undecylenic acid as its primary ingredient.  We set out key pros and cons below:


  • Undecylenic acid is a ‘natural’ product derived from caster oil.  It has been approved by the US FDA as an antifungal drug.
  • Zetaclear has not been associated with any severe side effects.
  • The nail treatment dries quickly on the surface of the nail and is non-staining.
  • The product is applied using a nail brush, much in the same way as a nail polish, so there is no need to touch the infection with the fingers.
  • The active ingredient is blended with a number of essential oils with known antimicrobial properties such as Tea Tree, Jojoba and Lavender oils.
  • Zetaclear has been designed specifically to penetrate deeply into the nail to reach the fungus.  It is only by direct contact that the fungus can be destroyed.


  • A twice daily application routine is recommended.  Many sufferers tire of having to apply Zetaclear once in the morning and once in the evening every day.  But without a consistent routine of therapy the treatment is unlikely to be successful.
  • Some doctors do not believe that Zetaclear can be effective in severe cases, where the fungus is very deeply embedded within the nail.
  • Many months of treatment are generally needed and it can take several weeks before there is any visible improvement to the condition of the nail.

In conclusion, it probably makes sense to use Zetaclear only for milder nail fungus infections, where the fungus has not spread across the entire nail.  It may also be useful as a combination therapy, used in conjunction with other treatment approaches.

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